| 2024-03 |
Nanoengineered Polymeric RNA Nanoparticles for Controlled Biodistribution and Efficient Targeted Cancer Therapy |
ACS Nano
|
| 2023-11 |
Targeting FLT3-TAZ signaling to suppress drug resistance in blast phase chronic myeloid leukemia |
Molecular Cancer
|
| 2023-07 |
A TEAD2-driven endothelial-like program shapes basal-like differentiation and metastasis of pancreatic cancer |
Gastroenterology
|
| 2023-03 |
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination |
Molecular Cancer
|
| 2022-07 |
Discovery of indirubin-3′-aminooxy-acetamide derivatives as potent and selective FLT3/D835Y mutant kinase inhibitors for acute myeloid leukemia |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
|
| 2021-08 |
Hot Spot Analysis of YAP-TEAD Protein-Protein Interaction Using the Fragment Molecular Orbital Method and Its Application for Inhibitor Discovery |
Cancers
|
| 2020-11 |
Synergistic antitumor activity of a DLL4/VEGF bispecific therapeutic antibody in combination with irinotecan in gastric cancer |
BMB REPORTS
|
| 2020-10 |
Cancer Metabolism: Phenotype, Signaling and Therapeutic Targets |
Cells
|
| 2020-09 |
Classifying the Linkage between Adipose Tissue Inflammation and Tumor Growth through Cancer-Associated Adipocytes |
MOLECULES AND CELLS
|
| 2020-08 |
Bee venom inhibits the proliferation and migration of cervical-cancer cells in an HPV E6/E7-dependent manner |
BMB REPORTS
|
| 2020-06 |
O-GlcNAcylation on LATS2 disrupts the Hippo pathway by inhibiting its activity |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2020-06 |
Discovery of orally active indirubin-3′-oxime derivatives as potent type 1 FLT3 inhibitors for acute myeloid leukemia |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
|
| 2020-03 |
Hypersensitivity to DNA double-strand breaks associated with PARG deficiency is suppressed by exo-1 and polq-1 mutations in Caenorhabditis elegans |
FEBS JOURNAL
|
| 2020-02 |
Three-dimensional imaging of cell and extracellular matrix elasticity using quantitative micro-elastography |
BIOMEDICAL OPTICS EXPRESS
|
| 2020-01 |
Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-Related Disorders |
CMGH Cellular and Molecular Gastroenterology and Hepatology
|
| 2019-12 |
Volume Adaptation Controls Stem Cell Mechanotransduction |
ACS APPLIED MATERIALS & INTERFACES
|
| 2019-06 |
Regulation of TEAD Transcription Factors in Cancer Biology |
Cells
|
| 2019-03 |
MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity |
MOLECULAR CELL
|
| 2018-08 |
RAP2 mediates mechanoresponses of the Hippo pathway |
NATURE
|
| 2018-07 |
Regulation of the Hippo pathway in cancer biology |
CELLULAR AND MOLECULAR LIFE SCIENCES
|
| 2018-02 |
The Role of Hippo Pathway in Cancer Stem Cell Biology |
MOLECULES AND CELLS
|
| 2017-11 |
Regulation of the Hippo Pathway Transcription Factor TEAD |
TRENDS IN BIOCHEMICAL SCIENCES
|
| 2017-08 |
Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation |
NATURE CELL BIOLOGY
|
| 2017-04 |
eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth |
CANCER RESEARCH
|
| 2015-10 |
MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway |
NATURE COMMUNICATIONS
|
| 2015-08 |
Alternative Wnt Signaling Activates YAP/TAZ |
CELL
|
| 2015-06 |
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis |
GENES & DEVELOPMENT
|
| 2015-04 |
Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway |
NATURE CELL BIOLOGY
|
| 2015-01 |
Differential regulation of mTORC1 by leucine and glutamine |
SCIENCE
|
| 2014-07 |
Rag GTPases are cardioprotective by regulating lysosomal function |
NATURE COMMUNICATIONS
|
| 2014-07 |
Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis |
PLOS GENETICS
|
| 2014-06 |
The Hippo signaling pathway in stem cell biology and cancer |
EMBO REPORTS
|
| 2013-10 |
Regulation of the Hippo pathway and implications for anticancer drug development |
TRENDS IN PHARMACOLOGICAL SCIENCES
|
| 2013-08 |
WNK4 inhibits plasma membrane targeting of NCC through regulation of syntaxin13 SNARE formation. |
CELLULAR SIGNALLING
|
| 2013-07 |
ULK1 induces autophagy by phosphorylating Beclin-1 and activating Vps34 lipid kinase |
NATURE CELL BIOLOGY
|
| 2013-06 |
Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation |
GENES & DEVELOPMENT
|
| 2013-01 |
Dynamic modulation of ANO1/TMEM16A HCO3- permeability by Ca2+/calmodulin |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2012-12 |
Expression of Anion Exchangers in Cultured Human Endolymphatic Sac Epithelia |
OTOLOGY & NEUROTOLOGY
|
| 2012-10 |
Transepithelial Bicarbonate Secretion: Lessons from the Pancreas. |
Cold Spring Harbor Perspectives in Medicine
|
| 2012-04 |
Opposite regulatory effects of TRPC1 and TRPC5 on neurite outgrowth in PC12 cells |
CELLULAR SIGNALLING
|
| 2012-01 |
MOLECULAR MECHANISM OF PANCREATIC AND SALIVARY GLAND FLUID AND HCO3- SECRETION |
PHYSIOLOGICAL REVIEWS
|
| 2011-06 |
Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2011-03 |
WNK4 kinase negatively regulates the surface expression of Muscarinic M3 receptor |
CELLULAR SIGNALLING
|
| 2010-08 |
Dynamic Regulation of CFTR Bicarbonate Permeability by [Cl-](i) and Its Role in Pancreatic Bicarbonate Secretion |
Gastroenterology
|
| 2010-03 |
beta Pix Up-regulates Na+/H+ Exchanger 3 through a Shank2-mediated Protein-Protein Interaction |
The Journal of biological chemistry
|
| 2009-12 |
PDZ-based adaptor proteins in epithelial anion transport and VIP receptor regulation |
The Journal Of Medical Investigation : Jmi
|
| 2009-08 |
Synaptic Scaffolding Molecule Binds to and Regulates Vasoactive Intestinal Polypeptide Type-1 Receptor in Epithelial Cells |
Gastroenterology
|