| 2024-02 |
Inhibition of protein-protein interactions using biodegradable depsipeptide nanoassemblies |
Journal of Controlled Release
|
| 2023-12 |
Inhibition of chloride intracellular channel protein 1 (CLIC1) ameliorates liver fibrosis phenotype by activating the Ca2+-dependent Nrf2 pathway |
Biomedicine & Pharmacotherapy
|
| 2023-11 |
NDUFA12 as a Functional Target of the Anticancer Compound Ertredin in Human Hepatoma Cells As Revealed by Label-Free Chemical Proteomics |
Journal of Proteome Research
|
| 2023-09 |
11th Asia Oceania Human Proteome Organization Congress Report |
Molecular and Cellular Proteomics
|
| 2023-07 |
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones |
International Journal of Biological Sciences
|
| 2023-07 |
Spatially Resolved Proteomic and Transcriptomic Profiling of Anaplastic Lymphoma Kinase-Rearranged Pulmonary Adenocarcinomas Reveals Key Players in Inter- and Intratumoral Heterogeneity |
International Journal of Molecular Sciences
|
| 2022-12 |
The Second Asia-Oceania Human Proteome Organization (AOHUPO) Online Education Series on the Renaissance of Clinical Proteomics: Biomarkers, Imaging and Therapeutics |
Molecular and Cellular Proteomics
|
| 2022-12 |
Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID |
Cell Chemical Biology
|
| 2022-04 |
Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction |
Clinical and Translational Medicine
|
| 2022-04 |
Mitochondrial ROS Produced in Human Colon Carcinoma Associated with Cell Survival via Autophagy |
Cancers
|
| 2021-11 |
Development of Novel VEGFR2 Inhibitors Originating from Natural Product Analogues with Antiangiogenic Impact |
JOURNAL OF MEDICINAL CHEMISTRY
|
| 2021-10 |
Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein |
AUTOPHAGY
|
| 2021-09 |
A natural small molecule induces MAPT clearance via mTOR-independent autophagy |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2021-08 |
Activation of Ca2+-AMPK-mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts |
Clinical and translational medicine
|
| 2021-08 |
A biobanking turning-point in the use of formalin-fixed paraffin tumor blocks to unveil kinase signaling in melanoma |
Clinical and translational medicine
|
| 2021-07 |
Daptomycin suppresses tumor migration and angiogenesis via binding to ribosomal protein S19 in humans |
JOURNAL OF ANTIBIOTICS
|
| 2021-07 |
The human melanoma proteome atlas—Defining the molecular pathology |
Clinical and translational medicine
|
| 2021-07 |
The Human Melanoma Proteome Atlas—Complementing the melanoma transcriptome |
Clinical and translational medicine
|
| 2021-07 |
Matrix-assisted laser desorption ionization - mass spectrometry imaging of erlotinib reveals a limited tumor tissue distribution in a non-small-cell lung cancer mouse xenograft model |
Clinical and translational medicine
|
| 2021-06 |
Enhanced production of clavulanic acid by improving glycerol utilization using reporter-guided mutagenesis of an industrial Streptomyces clavuligerus strain |
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
|
| 2021-02 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) |
AUTOPHAGY
|
| 2021-02 |
Functional inhibition of fatty acid binding protein 4 ameliorates impaired ciliogenesis in GCs |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2021-01 |
Asia-oceania HUPO: Past, Present, and Future |
MOLECULAR & CELLULAR PROTEOMICS
|
| 2021-01 |
Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction |
COMMUNICATIONS BIOLOGY
|
| 2021-00 |
Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein |
AUTOPHAGY
|
| 2020-12 |
Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction |
BMB REPORTS
|
| 2020-09 |
Dna polymerase alpha subunit b is a binding protein for erlotinib resistance in non-small cell lung cancer |
Cancers
|
| 2020-09 |
Targeting Autophagy In Disease: Recent Advances In Drug Discovery |
EXPERT OPINION ON DRUG DISCOVERY
|
| 2020-06 |
Proteomic analysis enables distinction of early- versus advanced-stage lung adenocarcinomas |
Clinical and translational medicine
|
| 2020-06 |
Novel functional proteins coded by the human genome discovered in metastases of melanoma patients |
CELL BIOLOGY AND TOXICOLOGY
|
| 2020-04 |
Identification and validation of VEGFR2 kinase as a target of voacangine by a systematic combination of DARTS and MSI |
Biomolecules
|
| 2020-03 |
Protein expression in metastatic melanoma and the link to disease presentation in a range of tumor phenotypes |
Cancers
|
| 2020-03 |
Autophagic inhibition via lysosomal integrity dysfunction leads to antitumor activity in glioma treatment |
Cancers
|
| 2020-02 |
MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer |
SCIENTIFIC REPORTS
|
| 2020-01 |
Proteomic analyses reveal that ginsenoside Rg3(S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin |
JOURNAL OF GINSENG RESEARCH
|
| 2020-00 |
Profiling the Protein Targets of Unmodified Bio-Active Molecules with Drug Affinity Responsive Target Stability and Liquid Chromatography/Tandem Mass Spectrometry |
PROTEOMICS
|
| 2019-12 |
The hidden story of heterogeneous B-raf V600E mutation quantitative protein expression in metastatic melanoma—association with clinical outcome and tumor phenotypes |
Cancers
|
| 2019-08 |
Clinical protein science in translational medicine targeting malignant melanoma |
CELL BIOLOGY AND TOXICOLOGY
|
| 2019-08 |
Improved production of clavulanic acid by reverse engineering and overexpression of the regulatory genes in an industrial Streptomyces clavuligerus strain |
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
|
| 2019-06 |
Design, synthesis, and biological evaluation of novel pyrrolo[1,2-a]pyrazine derivatives |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2019-04 |
Reverse Chemical Proteomics Identifies an Unanticipated Human Target of the Antimalarial Artesunate |
ACS CHEMICAL BIOLOGY
|
| 2019-03 |
Acid ceramidase, an emerging target for anti-cancer and anti-angiogenesis |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2019-01 |
A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase |
ACS CHEMICAL BIOLOGY
|
| 2018-08 |
Biobank integration of large‑scale clinical and histopathology melanoma studies within the European Cancer Moonshot Lund Center |
Clinical and translational medicine
|
| 2018-08 |
Endogenous expression mapping of malignant melanoma by mass spectrometry imaging |
Clinical and translational medicine
|
| 2018-08 |
Eupatilin rescues ciliary transition zone defects to ameliorate ciliopathy-related phenotypes |
JOURNAL OF CLINICAL INVESTIGATION
|
| 2018-08 |
Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway |
SCIENTIFIC REPORTS
|
| 2018-06 |
Astemizole inhibits mTOR signaling and angiogenesis by blocking cholesterol trafficking |
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
|
| 2018-04 |
A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes. |
NATURE COMMUNICATIONS
|
| 2018-01 |
Chemical proteomics, an integrated research engine for exploring drug-target-phenotype interactions |
PROTEOME SCIENCE
|
| 2018-01 |
Downregulation of mitochondrial UQCRB inhibits cancer stem cell-like properties in glioblastoma |
INTERNATIONAL JOURNAL OF ONCOLOGY
|
| 2017-12 |
Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham |
KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES
|
| 2017-12 |
Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress |
SCIENTIFIC REPORTS
|
| 2017-11 |
Mitochondrial UQCRB as a new molecular prognostic biomarker of human colorectal cancer |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2017-11 |
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth |
CANCER LETTERS
|
| 2017-09 |
Two cyclic hexapeptides from Penicillium sp. FN070315 with antiangiogenic activities |
PLOS ONE
|
| 2017-09 |
Approaches for discovering novel bioactive small molecules targeting autophagy |
EXPERT OPINION ON DRUG DISCOVERY
|
| 2017-07 |
Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans |
PROTEOME SCIENCE
|
| 2017-04 |
The effect of indatraline on angiogenesis suppression through HIF-1α-mediated VEGF inhibition |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2017-01 |
FK506, an Immunosuppressive Drug, Induces Autophagy by Binding to the V-ATPase Catalytic Subunit A in Neuronal Cells |
JOURNAL OF PROTEOME RESEARCH
|
| 2016-10 |
Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway. |
SCIENTIFIC REPORTS
|
| 2016-08 |
Turmeric extract and its active compound, curcumin, protect against chronic CCl4-induced liver damage by enhancing antioxidation |
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
|
| 2016-08 |
Inhibition of 5-lipoxygenase suppresses vascular endothelial growth factor-induced angiogenesis in endothelial cells. |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2016-08 |
Tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, exhibits potent antiangiogenic activity in vitro |
INTERNATIONAL JOURNAL OF ONCOLOGY
|
| 2016-05 |
Building the basis for proteomics in personalized medicine for targeted treatment |
Clinical and translational medicine
|
| 2016-03 |
Advances in identification and validation of protein targets of natural products without chemical modification |
NATURAL PRODUCT REPORTS
|
| 2016-03 |
Discovery of novel drug targets and their functions using phenotypic screening of natural products |
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
|
| 2016-01 |
Identification of a resveratrol tetramer as a potent hepatitis C virus helicase inhibitor |
BRITISH JOURNAL OF PHARMACOLOGY
|
| 2015-09 |
Preface to this special issue on chemical biology and drug |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2015-09 |
Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2015-09 |
Antiangiogenic activity of herboxidiene via downregulation of vascular endothelial growth factor receptor-2 and hypoxia-inducible factor-1a |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2015-09 |
Drug compound characterization by mass spectrometry imaging in cancer tissue |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2015-09 |
Cell-permeable mitochondrial ubiquinol-cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo |
CANCER LETTERS
|
| 2015-07 |
The small molecule R-(-)-β-O-methylsynephrine binds to nucleoporin 153 kDa and inhibits angiogenesis |
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
|
| 2015-05 |
NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction |
JOURNAL OF MOLECULAR MEDICINE-JMM
|
| 2015-03 |
Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice |
ONCOTARGET
|
| 2015-03 |
Antiangiogenic Activity of the Lipophilic Antimicrobial Peptides from an Endophytic Bacterial Strain Isolated from Red Pepper Leaf |
MOLECULES AND CELLS
|
| 2015-02 |
HIF-1α suppressing small molecule, LW6, inhibits cancer cell growth by binding to calcineurin b homologous protein 1 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2015-01 |
The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cells |
BMC CANCER
|
| 2015-01 |
A non-immunosuppressive FK506 analogue with neuroregenerative activity produced from a genetically engineered Streptomyces strain |
RSC ADVANCES
|
| 2014-12 |
A mutation in the mitochondrial protein UQCRB promotes angiogenesis through the generation of mitochondrial reactive oxygen species |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2014-11 |
A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic cells |
BRITISH JOURNAL OF PHARMACOLOGY
|
| 2014-10 |
A histone demethylase inhibitor, methylstat, inhibits angiogenesis in vitro and in vivo |
RSC ADVANCES
|
| 2014-10 |
Development of a Novel Class of Mitochondrial Ubiquinol-Cytochrome c Reductase Binding Protein (UQCRB) Modulators as Promising Antiangiogenic Leads |
JOURNAL OF MEDICINAL CHEMISTRY
|
| 2014-10 |
The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3 beta and ERK1/2 signaling pathway |
EXPERIMENTAL CELL RESEARCH
|
| 2014-07 |
Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2014-05 |
The 7th Japan-Korea Chemical Biology Symposium: Chemical Biology of Natural Bioactive Molecules |
ACS CHEMICAL BIOLOGY
|
| 2014-03 |
Convallatoxin, a Dual Inducer of Autophagy and Apoptosis, Inhibits Angiogenesis In Vitro and In Vivo |
PLOS ONE
|
| 2014-01 |
Anti-Obesity Phenotypic Screening Looking to Increase OBR Cell Surface Expression |
JOURNAL OF BIOMOLECULAR SCREENING
|
| 2013-11 |
A new anti-angiogenic small molecule, G0811, inhibits angiogenesis via targeting hypoxia inducible factor (HIF)-1α signal transduction |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2013-09 |
Mitochondrial UQCRB regulates VEGFR2 signaling in endothelial cells |
JOURNAL OF MOLECULAR MEDICINE-JMM
|
| 2013-07 |
Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay |
PLOS ONE
|
| 2013-05 |
Mutational biosynthesis of a FK506 analogue containing a non-natural starter unit |
MOLECULAR BIOSYSTEMS
|
| 2013-02 |
Functional inhibition of UQCRB suppresses angiogenesis in zebrafish |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2013-02 |
Exploring the role of mitochondrial UQCRB in angiogenesis using small molecules |
MOLECULAR BIOSYSTEMS
|
| 2013-02 |
Discovery of Pyridone-Based Histone Deacetylase Inhibitors: Approaches for Metabolic Stability |
CHEMMEDCHEM
|