| 2012-12 |
Property-Based Optimization of Hydroxamate-Based gamma-Lactam HDAC Inhibitors to Improve Their Metabolic Stability and Pharmacokinetic Profiles |
JOURNAL OF MEDICINAL CHEMISTRY
|
| 2012-04 |
Guidelines for the use and interpretation of assays for monitoring autophagy |
AUTOPHAGY
|
| 2012-04 |
Verrulactones A and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375 |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2012-04 |
Matairesinol inhibits angiogenesis via suppression of mitochondrial reactive oxygen species |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2012-03 |
Identification and validation of bioactive small molecule target through phenotypic screening |
BIOORGANIC & MEDICINAL CHEMISTRY
|
| 2012-03 |
Identification of EBP50 as a Specific Biomarker for Carcinogens Via the Analysis of Mouse Lymphoma Cellular Proteome |
Molecules and Cells
|
| 2012-02 |
Moesin Is a Biomarker for the Assessment of Genotoxic Carcinogens in Mouse Lymphoma |
Molecules and Cells
|
| 2012-01 |
A natural small molecule voacangine inhibits angiogenesis both in vitro and in vivo |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2011-11 |
화학생물학의 지난 십년과 새로운 미래 |
바이오인
|
| 2011-11 |
생리활성 저분자 화합물의 작용기전 해석 : 화학과 생물학의 만남 |
바이오인
|
| 2011-09 |
The sphingosine-1-phosphate derivative NHOBTD inhibits angiogenesis both in vitro and in vivo |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2011-02 |
Potential anti-cancer activity of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a histone deacetylase inhibitor, against breast cancer both in vitro and in vivo |
CANCER SCIENCE
|
| 2011-02 |
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues |
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
|
| 2011-02 |
Identification of a novel small molecule targeting UQCRB of mitochondrial complex III and its anti-angiogenic activity |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2011-01 |
Identification and biological activities of a new antiangiogenic small molecule that suppresses mitochondrial reactive oxygen species |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2010-12 |
An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67 |
PHYTOCHEMISTRY LETTERS
|
| 2010-12 |
Control of Autophagy with Small Molecules |
Archives Of Pharmacal Research
|
| 2010-12 |
Identification of genes related to a synergistic effect of taxane and suberoylanilide hydroxamic acid combination treatment in gastric cancer cells |
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
|
| 2010-08 |
R-(-)-beta-O-methylsynephrine, a natural product, inhibits VEGF-induced angiogenesis in vitro and in vivo |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2010-08 |
A Novel Ca2+/Calmodulin Antagonist HBC Inhibits Angiogenesis and Down-regulates Hypoxia-inducible Factor |
The Journal of biological chemistry
|
| 2010-04 |
Terpestacin Inhibits Tumor Angiogenesis by Targeting UQCRB of Mitochondrial Complex III and Suppressing Hypoxia-induced Reactive Oxygen Species Production and Cellular Oxygen Sensing |
The Journal of biological chemistry
|
| 2010-03 |
Autophagonizer, a novel synthetic small molecule, induces autophagic cell death |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2010-02 |
Confocal-Based Method for Quantification of Diffusion Kinetics in Microwell Plates and Its Application for Identifying a Rapid Mixing Method for High-Content/Throughput Screening |
Journal Of Biomolecular Screening
|
| 2010-01 |
NBBA, a synthetic small molecule, inhibits TNF-alpha-induced angiogenesis by suppressing the NF-kappa B signaling pathway |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2009-08 |
Overexpression of metastasis-associated protein 2 is associated with hepatocellular carcinoma size and differentiation |
Journal Of Gastroenterology And Hepatology
|
| 2009-04 |
Identification and validation of calmodulin as a binding protein of an anti-proliferative small molecule 3,4-dihydroisoquinolinium salt |
Proteomics Clinical Applications
|
| 2009-04 |
N-Hydroxy-7-(2-naphthylthio) Heptanomide Inhibits Retinal and Choroidal Angiogenesis |
Molecular Pharmaceutics
|
| 2009-03 |
The effect of xanthorrhizol on the expression of matrix metalloproteinase-1 and type-I procollagen in ultraviolet-irradiated human skin fibroblasts |
Phytotherapy Research
|
| 2008-11 |
Hydroxamic Acid Derivatives of Mycophenolic Acid Inhibit Histone Deacetylase at the Cellular Level |
Bioscience Biotechnology And Biochemistry
|
| 2008-09 |
The non-provitarnin A carotenoid, lutein, inhibits NF-kappa B-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappa B-inducing kinase pathways: Role of H2O2 in NF-kappa B activation |
Free Radical Biology And Medicine
|
| 2008-09 |
Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp KORDI-3973 |
Phytochemistry
|
| 2008-08 |
Hot springs and cool natural products |
Nature Chemical Biology
|
| 2008-07 |
Global and focused transcriptional profiling of small molecule aminopeptidase N inhibitor reveals its mechanism of angiogenesis inhibition |
Biochemical And Biophysical Research Communications
|
| 2008-05 |
Inhibition of histone deacetylase1 induces autophagy |
Biochemical And Biophysical Research Communications
|
| 2008-05 |
Downregulation of melanin synthesis by haginin A and its application to in vivo lightening model |
Journal Of Investigative Dermatology
|
| 2008-04 |
Molecular mechanism of ADP-ribosyl cyclase activation in angiotensin II signaling in murine mesangial cells |
American Journal Of Physiology-Renal Physiology
|
| 2008-03 |
Inhibition of choroidal neovascularization by homoisoflavanone, a new angiogenesis inhibitor |
Molecular Vision
|
| 2008-02 |
Genome-wide drug-induced haploinsufficient screening of fission yeast for identification of hydrazinocurcumin targets |
Journal Of Microbiology And Biotechnology
|
| 2007-12 |
Homoisoflavanone inhibits retinal neovascularization through cell cycle arrest with decrease of cdc2 expression |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-12 |
Functional analysis of a histone deacetylase-like protein of Thermus caldophilus GK24 in mammalian cell |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-12 |
Potent inhibition of in vivo angiogenesis and tumor growth by a novel cyclooxygenase-2 inhibitor, enoic acanthoic acid |
CANCER SCIENCE
|
| 2007-12 |
Proteomic analysis of microvesicles derived from human colorectal cancer cells |
JOURNAL OF PROTEOME RESEARCH
|
| 2007-11 |
Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-11 |
Modification of cap group in δ-lactam-based histone deacetylase (HDAC) inhibitors |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2007-09 |
Cloning, expression, and biochemical characterization of a new histone deacetylase-like protein from Thermus caldophilus GK24 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-09 |
Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells |
BIOLOGICAL & PHARMACEUTICAL BULLETIN
|
| 2007-08 |
Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110 |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2007-08 |
Discovery of gliotoxin as a new small molecule targeting thioredoxin redox system |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-08 |
Streptochlorin, a marine natural product, inhibits NF-kappaB activation and suppresses angiogenesis in vitro. |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2007-08 |
Development of a new Ca2+/calmodulin antagonist and its anti-proliferative activity against colorectal cancer cells |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-04 |
Anti-tumor activity of N-hydroxy-7-(2-naphthylthio) heptanomide, a novel histone deacetylase inhibitor |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-03 |
Synthesis and biological activity of fungal metabolite, 4-hydroxy-3-(3′-methyl-2′-butenyl)-benzoic acid |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2007-02 |
Embellistatin, a microtubule polymerization inhibitor, inhibits angiogenesis both in vitro and in vivo |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2007-02 |
Psammaplin A is a natural prodrug that inhibits class I histone deacetylase |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2006-12 |
Discovery of a small-molecule inhibitor for kidney ADP-ribosyl cyclase: Implication for intracellular calcium signal mediated by cyclic ADP-ribose |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2006-12 |
Discovery of a small-molecule inhibitor for kidney ADP-ribosyl cyclase: Implication for intracellula |
EXP. MOL. MED.
|
| 2006-10 |
4-O-Methylgallic acid suppresses inflammation-associated gene expression by inhibition of redox-based NF-κB activation |
INTERNATIONAL IMMUNOPHARMACOLOGY
|
| 2006-10 |
4-O-methylgallic acid down-regulates endothelial adhesion molecule expression by inhibiting NF-κB-DNA-binding activity |
EUROPEAN JOURNAL OF PHARMACOLOGY
|
| 2006-06 |
화학유전체학: 기능유전체학 및 신약개발을 위한 통합적 연구수단 |
대한 생화학.분자생물학회 소식지
|
| 2006-05 |
Chemical genomics with natural products |
J. MICROBIOL. BIOTECHNOL.
|
| 2006-04 |
Discovery of new small molecules and targets towards angiogenesis via chemical genomics approach |
CURRENT DRUG TARGETS
|
| 2006-04 |
Rengyolone inhibits inducible nitric oxide synthase expression and nitric oxide production by down-regulation of NF-κB and p38 MAP kinase activity in LPS-stimulated RAW 264.7 cells |
BIOCHEMICAL PHARMACOLOGY
|
| 2006-01 |
Gentisyl alcohol, an antioxidant from microbial metabolite, induces angiogenesis in vitro |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2005-11 |
Focal adhesion kinase regulates syndecan-2-mediated tumorigenic activity of HT1080 fibrosarcoma cells |
CANCER RESEARCH
|
| 2005-11 |
Trichostatin A exacerbates atherosclerosis in low density lipoprotein receptor-deficient mice |
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
|
| 2005-10 |
Coordinated transcriptional regulation of calmegin,a testis-specific molecular chaperon, by histonedeacetylase and CpG methyltransferase |
EXP. MOL. MED.
|
| 2005-08 |
Development of an angiogenesis-focused cDNA chip and validation of its functionality |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2005-07 |
FBI-1 enhances transcription of the nuclear factor-κB (NF-κB)-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-κB |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2005-06 |
Gentisyl alcohol inhibits apoptosis by suppressing caspase activity induced by etoposide |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2005-05 |
Hepatic steatosis in transgenic mice overexpressing human histone deacetylase 1 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2005-05 |
Antiangiogenic activity of 4-0-methylgallic acid from Canavalia gladiata, a dietary legume |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2005-04 |
Cryptotanshinone but not tanshinone IIA inhibits angiogenesis in vitro |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2005-04 |
유전체 기능 및 신약개발 연구의 새흐름, 화학 유전체학 (Chemical Genomics) |
BIO-MEDICAL SCIENCE
|
| 2005-04 |
화학과 생명과학의 융합학문으로서 화학 유전체학 |
화학세계
|
| 2005-01 |
Chemical genomics on new angiogenesis inhibitors |
TANPAKUSHITSU KAKUSAN KOSO PROTEIN,NUCLEIC ACID, ENZYME
|
| 2005-01 |
Trichostatin A attenuates airway inflammation in mouse asthma model |
CLINICAL AND EXPERIMENTAL ALLERGY
|
| 2005-01 |
A new synthetic analogue of thymidine, 7-(3-bromo-phenoxy)-thymidine, inhibits the proliferation of tumor cells |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2005-01 |
N-Hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2004-12 |
Transgenic expression of Korean type hepatitis C virus core protein and related mutants in mice |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2004-12 |
Chemical genetics for therapeutic target mining |
EXPERT OPINION ON THERAPEUTIC TARGETS
|
| 2004-11 |
Modified oligonucleotides containing lithocholic acid in their backbones: Their enhanced cellular uptake and their mimicking of hairpin structures |
CHEMBIOCHEM
|
| 2004-10 |
A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function |
CHEMISTRY & BIOLOGY
|
| 2004-09 |
Cell cycle inhibitory activity of 4-hydroxy-3(3 '-methyl-2 '-butenyl)-benzoic acid from Curvularia sp KF |
JOURNAL OF ANTIBIOTICS
|
| 2004-03 |
Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells |
ONCOGENE
|
| 2004-02 |
Anti-angiogenic activity of a homoisoflavanone from Cremastra appendiculata |
PLANTA MEDICA
|
| 2004-02 |
Downregulation of gelsolin and retinoic acid receptor beta expression in gastric cancer tissues through histone deacetylase 1 |
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
|
| 2004-01 |
Psammaplin A, a marine natural product, inhibits aminopeptidase N and suppresses angiogenesis in vitro |
CANCER LETTERS
|
| 2003-11 |
Inhibitory activity of diacylglycerol acyltransferase by cochlioquinones A and A1 |
JOURNAL OF ANTIBIOTICS
|
| 2003-10 |
Association of sustained ERK activity with integrin beta3 induction during receptor activator of nuclear factor kappaB ligand (RANKL)-directed osteoclast differentiation |
EXPERIMENTAL CELL RESEARCH
|
| 2003-08 |
Irreversible inhibition of CD13/aminopeptidase N by the antiangiogenic agent curcumin |
CHEMISTRY & BIOLOGY
|
| 2003-01 |
Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1, 2 and 3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture |
PLANT JOURNAL
|
| 2003-01 |
Post genomics 시대에 있어 chemical genomics (화학유전체학) 연구의 역할 |
보건산업기술동향지
|
| 2003-01 |
Isolation of Streptomyces sp. KK565 as a Producer of β-Amyloid Aggregation Inhibitor |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2003-01 |
Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1 activity |
BBRC
|
| 2003-01 |
Histone Deacetylase in Carcinogenesis and Its Inhibitors as Anti-cancer Agents |
JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
|
| 2003-01 |
Evaluation of plant-derived compounds as natural herbicidal agents |
Kor J Weed Sci
|
| 2003-01 |
Decreased syndecan-2 expression correlates with trichostatin-A induced-morphological changes and reduced tumorigenic activity in colon carcinoma cells |
ONCOGENE
|